Data from: High-resolution single-cell analyses reveal evolutionary constraints and evolvability of sexual circuits in Drosophila

To understand how the cellular and molecular composition of neural
circuits evolves to generate species-specific behaviors, we performed
single-cell transcriptomic profiling of sexual circuits labeled by the sex
determination gene doublesex (dsx) in adult males of four Drosophila
species: D. melanogaster, D. yakuba, D. santomea, and D. teissieri. Using
this dataset, we compared molecularly defined dsx⁺ cell types across
species, quantified transcriptomic divergence within each cell type, and
analyzed differences in gene expression. In addition, we characterized sex
differences in dsx⁺ neurons by generating a single-cell transcriptomic
dataset from adult females of D. melanogaster, enabling us to examine
species divergence in the context of sexual dimorphism. These datasets are
shared here for public access.