ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03)

Protein Data Bank Japan2024-01-17 更新2026-03-21 收录

抗体-抗原复合物晶体结构

类风湿性关节炎免疫

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ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03) Descriptor: IA03 peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,IA03 peptide containing the citrullinated C1 epitope of collagen type II, heavy chain of ACC1 antibody Fab fragment, light chain of ACC1 antibody Fab fragment Authors: Dobritzsch, D, Holmdahl, R, Ge, C. Deposit date: 2017-01-11 Release date: 2017-07-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017

ACC1 Fab片段与II型胶原（CII）的瓜氨酸化C1表位（IA03）形成的复合物描述项：包含II型胶原瓜氨酸化C1表位的IA03肽、胶原α1(II)链、包含II型胶原瓜氨酸化C1表位的IA03肽、ACC1抗体Fab片段重链、ACC1抗体Fab片段轻链作者：Dobritzsch D、Holmdahl R、Ge C 存储日期：2017-01-11 发布日期：2017-07-19 最后修改日期：2024-01-17 实验方法：X射线衍射（2.7 Å）引用文献：《抗瓜氨酸化蛋白抗体通过与关节软骨交叉反应引发关节炎》，JCI Insight, 2, 2017

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2017-01-11

ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03)

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