five

Gut Microbiome IMS-MS Experiments

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DataCite Commons2023-07-06 更新2025-04-17 收录
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https://panoramaweb.org/BakerMCBA.url
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资源简介:
Bile acids play key roles in nutrient uptake, inflammation, signaling, and microbiome composition. While previous bile acid analyses have primarily focused on profiling 5 canonical primary and secondary bile acids and their glycine and taurine bile acid-amino acid (BA-AA) conjugates, recent studies suggest that many other microbial conjugated BA-AAs (or MCBAs) exist. MCBAs are produced by the gut microbiota and serve as biomarkers providing information about early disease onset and gut health. Here we analyzed 8 core bile acids synthetically conjugated with 22 proteogenic and non-proteogenic amino acids totaling 176 MCBAs to make an MCBA library, and applied this library to evaluate two model systems.
提供机构:
Panorama Public
创建时间:
2023-07-06
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