A comprehensive phylogenomic platform for exploring the angiosperm Tree of Life

Abstract The tree of life is the fundamental biological roadmap for navigating the evolution and properties of life on Earth, and yet remains largely unknown. Even angiosperms (flowering plants) are fraught with data gaps, despite their critical role in sustaining terrestrial life. Today, high-throughput sequencing promises to significantly deepen our understanding of evolutionary relationships. Here, we describe a comprehensive phylogenomic platform for exploring the angiosperm tree of life, comprising a set of open tools and data based on the 353 nuclear genes targeted by the universal Angiosperms353 sequence capture probes. The primary goals of this article are to (i) document our methods, (ii) describe our first data release, and (iii) present a novel open data portal, the Kew Tree of Life Explorer (https://treeoflife.kew.org). We aim to generate novel target sequence capture data for all genera of flowering plants, exploiting natural history collections such as herba..., See Materials and Methods in corresponding paper. ,摘要 生命之树是解析地球上生命演化历程与性状特征的核心生物学路线图，但目前仍有大量未知之处。即便对于被子植物（Angiosperms，开花植物）而言，尽管它们在维持陆地生态系统运转中发挥着至关重要的作用，相关数据空白仍比比皆是。如今，高通量测序技术有望大幅深化我们对物种演化关系的认知。本研究构建了一套用于解析被子植物生命之树的综合系统发育基因组学平台，该平台基于通用的Angiosperms353序列捕获探针所靶向的353个核基因，整合了一系列开放工具与数据集。本文的核心目标有三：其一，详述本研究的实验方法；其二，介绍首批公开的数据集；其三，推出全新的开放数据门户——邱园生命之树探索平台（Kew Tree of Life Explorer，网址：https://treeoflife.kew.org）。本研究计划利用标本馆等自然历史馆藏资源，为所有被子植物属级类群获取全新的靶向序列捕获数据，详细内容参见对应论文的材料与方法部分。