Bulk RNA-seq of Quiescent and Nutlin3a-Induced Senescent mouse pulmonary fibroblasts
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198397
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Purpose: Use RNA-seq strategy to characterize the differentially expressed genes and significant transposable elements in quiescent and nutlin3a-induced senescent pulmonary fibroblasts to identify the factors and possible neoantigens in activating the cytotoxic T cell immunity. Methods: FACSorted primary pulmonary fibroblasts were utilized for the preparation of bulk RNA-seq libraries. Quiescence was induced by starvation and senescence was induced by nutlin 3a treatment. Examination of differentially expressed genes and significant transposable elements within quiescent and nutlin3a-induced senescent pulmonary fibroblasts
创建时间：
2022-11-11
