Condensation-Driven Assembly of Boron-Containing Bis(Heteroaryl) Motifs Using a Linchpin Approach
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://figshare.com/articles/dataset/Condensation_Driven_Assembly_of_Boron_Containing_Bis_Heteroaryl_Motifs_Using_a_Linchpin_Approach/2106895
下载链接
链接失效反馈官方服务：
资源简介：
Herein, we describe
the bromomethyl acyl boronate linchpin–an
enabling reagent for the condensation-driven assembly of novel bis(heteroaryl)
motifs. This building block is readily accessible from commercially
available starting materials. A variety of 2-amino- and 2-methylpyridines
were reacted with MIDA-protected bromomethyl acylboronate to afford
2-boryl imidazo[1,2-a]pyridine and 2-boryl
indolizine derivatives, respectively, in excellent yields. Subsequent
condensation with hydroxyamidines and hydrazonamides converted the
intermediate heterocycles into novel boron-containing bis(heteroaryl)
units characterized by high thermal stability.
创建时间：
2016-02-12
