Crystal structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 1.7 Angstrom; internal aldimine with PLP in the active site

Crystal structure of human Alanine:Glyoxylate Aminotransferase major allele (AGT-Ma) at 1.7 Angstrom; internal aldimine with PLP in the active site Descriptor: PYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase Authors: Giardina, G, Cutruzzola, F, Borri Voltattorni, C, Cellini, B, Montioli, R. Deposit date: 2015-12-10 Release date: 2016-12-21 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis. Sci Rep, 7, 2017

分辨率为1.7埃的人类丙氨酸:乙醛酸氨基转移酶主要等位基因（AGT-Ma）的晶体结构，其活性位点内存在与磷酸吡哆醛-5'-磷酸（PYRIDOXAL-5'-PHOSPHATE，简称PLP）结合形成的内部醛亚胺。描述项：磷酸吡哆醛-5'-磷酸、丝氨酸-丙酮酸氨基转移酶。作者：Giardina, G、Cutruzzola, F、Borri Voltattorni, C、Cellini, B、Montioli, R。提交日期：2015-12-10；发布日期：2016-12-21；最后修改日期：2024-01-10。实验方法：X射线衍射（X-RAY DIFFRACTION，1.7 Å）。引用文献：《人类丙氨酸:乙醛酸氨基转移酶活性位点的辐射损伤揭示催化过程中辅因子位置受到精细调控》，发表于《科学报告（Sci Rep）》，2017年，第7卷。