Brain transcriptional and epigenetic associations with the autistic phenotype
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This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
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2012-06-08
相关数据集
Methyl-CpG binding domain 2 (Mbd2) is an Epigenetic Regulator of Autism-Risk Genes and Cognition [ChIP-seq]. Methyl-CpG binding domain 2 (Mbd2) is an Epigenetic Regulator of Autism-Risk Genes and Cognition [ChIP-seq]
The Methyl-CpG-Binding Domain Protein family has been implicated in neurodevelopmental disorders. The Methyl-CpG-binding domain 2 (Mbd2) binds methylated DNA and was shown to play an important role in
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Knockdown of ASD risk genes leads to a shared transcriptional signature. Knockdown of ASD risk genes leads to a shared transcriptional signature
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Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism [WGS]. Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism [WGS]
Most autism spectrum disorder (ASD) cases involve complex genetics interacting with perinatal environment, complicating the discovery of common genetic risk. The epigenetic layer of DNA methylation sh
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Genome-wide DNA methylation analysis in autism spectrum disorders (ASD patients vs Controls)
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Bulk transcriptome analysis of Myt1l mutant mouse cortices across development.
We examined the effect of Myt1l deficiency in the cortices of mice during developement. Homozygous Myt1l deficiency resulted in postnatal lethality, and mutant mice presented gene expression changes a
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