Integrin alpha-5 beta-1 in complex with BIIG2 Fab
收藏Protein Data Bank Japan2025-10-22 更新2026-04-25 收录
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Integrin alpha-5 beta-1 in complex with BIIG2 Fab Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BIIG2 Fab Heavy Chain, ... Authors: Nguyen, A, Azumaya, C.M, Campbell, M.G. Deposit date: 2024-04-02 Release date: 2025-02-05 Last modified: 2025-10-22 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Shared ligand-blocking mechanism but distinct conformational modulation by alpha 5-targeting antibodies BIIG2 and MINT1526A. Biorxiv, 2025
整合素α5β1与BIIG2抗原结合片段（Fab）的复合物描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、BIIG2抗原结合片段重链……作者：Nguyen A、Azumaya C.M、Campbell M.G。入库日期：2024-04-02；发布日期：2025-02-05；最后修改日期：2025-10-22。实验方法：电子显微镜（2.6 Å）。引用文献：《靶向α5的抗体BIIG2与MINT1526A具有共通的配体阻断机制，但构象调控方式存在差异》，BioRxiv，2025
创建时间：
2024-04-02
