RlmR 23S rRNA methyltransferase from Thermus thermophilus in complex with methylated rRNA (Um2552) and S-adenosyl-L-homocysteine (SAH)

RlmR 23S rRNA methyltransferase from Thermus thermophilus in complex with methylated rRNA (Um2552) and S-adenosyl-L-homocysteine (SAH) Descriptor: 23S rRNA methyltransferase, RNA (59-MER), S-ADENOSYL-L-HOMOCYSTEINE, ... Authors: Tanouti, Y, Roovers, M, Droogmans, L, Van Elder, D, Kruys, V, Labar, G. Deposit date: 2025-01-14 Release date: 2025-04-23 Last modified: 2025-06-18 Method: X-RAY DIFFRACTION (2.006 Å) Cite: Structural insight into the novel Thermus thermophilus SPOUT methyltransferase RlmR catalysing Um2552 formation in the 23S rRNA A-loop: a case of convergent evolution. Nucleic Acids Res., 53, 2025嗜热栖热菌（Thermus thermophilus）来源的RlmR 23S核糖体RNA（23S rRNA）甲基转移酶，与甲基化rRNA（Um2552）及S-腺苷-L-高半胱氨酸（S-adenosyl-L-homocysteine, SAH）形成复合物。数据集描述：23S rRNA甲基转移酶、RNA（59聚体）、S-腺苷-L-高半胱氨酸……作者：Tanouti Y、Roovers M、Droogmans L、Van Elder D、Kruys V、Labar G。提交日期：2025-01-14；发布日期：2025-04-23；最后修改日期：2025-06-18。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.006埃。引用文献：《针对催化23S rRNA A环中Um2552形成的新型嗜热栖热菌SPOUT甲基转移酶（SPOUT methyltransferase）RlmR的结构解析：趋同进化一例》，《核酸研究（Nucleic Acids Res.）》，2025年，第53卷。