Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that
active PL: samples containing active CPD-photolyase, inactive PL: samples containing inactive CPD-photolyase.Summarized fold change values by microarray results of the selected 9 CPD-dependent genes.
C8orf33-proficient and deficient DIvA cells were treated with 4-hydroxy tamoxifen (4OHT) to induce DNA double strand breaks (DSB) at several loci within the human genome. following 4OHT treatment cell
