Gold vs Rhodium Catalysis: Tuning Reactivity through Catalyst Control in the C–H Alkynylation of Isoquinolones
收藏Figshare2016-02-29 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Gold_vs_Rhodium_Catalysis_Tuning_Reactivity_through_Catalyst_Control_in_the_C_H_Alkynylation_of_Isoquinolones/2300698
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A site-selective C-4/C-8 alkynylation of isoquinolones catalyzed by gold and rhodium complexes is reported. A broad range of synthetically useful functional groups (−F, −Cl, −Br, −CF3, −OMe, alkyl, etc.) were tolerated, providing an efficient and robust protocol for the synthesis either C-4- or C-8-alkynylated isoquinolones.
创建时间:
2016-02-29



