Supplementary Table S4 from Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes
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Feature-region combination AUCs and benchmarking
Sheet 1: Log2 fold-change, p-value, and q-value between ARPC and NEPC lines for central mean coverage in all queried (338) TFs (two tailed Mann-Whitney U test, Benjamini-Hochberg adjusted).
Sheet 2: 100-fold cross-validation AUCs for all region and feature combinations subset by the ‘AR10’ overlapping features (see Methods).
Sheet 3: 100-fold cross-validation AUCs for all region and feature combinations subset by the ‘Phenotype 47-defining’ overlapping features.
Sheet 4: 100-fold cross-validation AUCs for all region and feature combinations (global).
Sheet 5: Predictions scores, tumor fraction, depth of coverage, and subtype for benchmarking admixtures.
Sheet 6: AUCs for unsupervised prediction of admixture subtypes grouped by tumor fraction and depth.
Sheet 7: NEPC:ARPC ratio, tumor fraction, and ARPC and NEPC fraction predictions for mixed phenotype admixtures using Keraon (see Methods).
创建时间：
2023-03-01
