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LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [2_MARS_seq_B]

NIAID Data Ecosystem2026-05-01 收录

胚胎干细胞机械敏感性

LIS1基因表达调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198343 数据链接链接失效反馈

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资源简介：

We analyzed LIS1 dosage dependent gene expression changes in human embryonic stem cells. Bulk MARS-seq from LIS1 control and mutant hESCs.

应用场景：

创建时间：

2023-08-05

胚胎干细胞机械敏感性

LIS1基因功能

We analyzed LIS1 dosage dependent gene expression changes in human embryonic stem cells. Overall design: Bulk MARS-seq from LIS1 control and mutant hESCs.

NIAID Data Ecosystem20

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [3_seCLIP_seq]

胚胎干细胞机械敏感性

LIS1RNA结合特性

LIS1 dosage substantially affects gene expression, and we uncovered RNA binding properties in embryonic stem cells. Overall design: Two replicate seCLIP experiments were performed with LIS1 IP and two

NIAID Data Ecosystem00

LIS1 RNA binding orchestartes the mechanosensitive properties of embryonic stem cells in AGO2 dependent and independent ways.

胚胎干细胞机械敏感性

LIS1RNA结合调控

LIS1 immunoprecipitation in nuclear and cytoplasmic fractions of LIS1 Floxed/-, OE and WT embryonic stem cells. To identify AGO2 dependent and independent interactions LIS1 was immunoprecipitated in A

NIAID Data Ecosystem00

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [7_smRNA_B]. LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [7_smRNA_B]

胚胎干细胞机械敏感性

RNA表达调控

We analyzed small RNA expression changes in embryonic stem cells. Overall design: smallRNA expression profiling by high throughput sequencing in TT-FHAgo2 and TT-FHAgo2:LIS1-OE in mouse embryonic stem

NIAID Data Ecosystem10

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [7_smRNA_B]

胚胎干细胞机械敏感性

小RNA表达谱分析

We analyzed small RNA expression changes in embryonic stem cells. smallRNA expression profiling by high throughput sequencing in TT-FHAgo2 and TT-FHAgo2:LIS1-OE in mouse embryonic stem cells.

NIAID Data Ecosystem00

LIS1 RNA-binding orchestrates the mechanosensitive properties of embryonic stem cells in AGO2-dependent and independent ways [2_MARS_seq_B]

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