Blair-MER-Stacksfiles

All output files from Stacks analyses testing for bias in whole genome amplified DNA (using multiple displacement amplification; MDA) as compared to genomic DNA. Data include both sequencing runs and assemblies with and without the Microcebus murinus reference genome. Analyses are partitioned by tissue sample (e.g. MM1812). Within a single tissue sample, MDA and gDNA sequences are represented by different barcode sequences (see paper). Comparisons between treatments (gDNA vs. MDA) were performed at the SNP level.本数据集包含Stacks分析的全部输出文件，该分析用于对比基因组DNA（gDNA），检测采用多重置换扩增（multiple displacement amplification, MDA）得到的全基因组扩增DNA时的偏差。数据涵盖了使用与未使用小鼠狐猴（Microcebus murinus）参考基因组的测序流程及序列组装结果。分析按组织样本（如MM1812）进行分组。在同一组织样本中，MDA与gDNA序列通过不同的条码序列（barcode sequence）加以区分（详见论文）。两组处理（gDNA与MDA）间的比较基于单核苷酸多态性（single nucleotide polymorphism, SNP）水平开展。