Ly6C monocyte subsets transcriptome analysis from control and ApoE-/- mice
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https://www.ncbi.nlm.nih.gov/sra/SRP346765
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资源简介：
Inflammatory monocyte (MC) subset differentiation is a major feature in tissue inflammatory and atherosclerosis. The underlying molecular mechanism remains unclear. This study aims to explore molecule targets and signaling which determinate immunological features in MC subsets. ApoE-/- mice were fed a normal chow diet and switched to a high-fat (HF) diet at age 8 weeks and maintained on a HF diet for 12-14 weeks. The control C57BL/6 mice were fed a normal chow diet throughout. Blood Ly6Chigh and Ly6Clow MC subsets from control and ApoE-/- mice were isolated by flow cytometry sorting and subjected for bulk high-throughput RNA-sequencing. Overall design: Examination of 2 different monocyte in control (CT) and ApoE-/- mice
创建时间：
2022-01-12
