Colorectal cancer risk associated with macrogol laxative exposure compared to non-macrogol only exposure for each of the backdated analysis sets.

*OR = odds ratio. Covariates considered for adjustment included smoking status, alcohol drinking status, body mass index, socioeconomic status, inflammatory bowel disease, history of prior cancer (excluding CRC and basal cell carcinoma), diabetes, cholecystectomy, prescriptions for any of the following: aspirin, non-steroidal anti-inflammatory drugs, 5-aminosalicylic acid, statins, opioids, hormone replacement therapy, calcium supplements, dantron containing laxatives. Covariates were included in the final model where p≤0.05 or where the OR changed by >10%.