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Metabolic reprogramming of innate-like T cell fate and tissue homeostasis by PTEN [scRNA- and scTCR-seq]

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Developmental and metabolic signaling networks underpinning type-17 cell fate decisions in dictating tissue homeostasis versus fatal autoimmunity We used scRNA-seq and scTCR-seq to profile CCR6+CD127+TCRb+ thymocytes of wild-type mice and mice with PTEN T cell-specific knockout and heterozygous.

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