Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=aa0944435842856b61210f080021543d
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资源简介：
The results from our study have identified two clinically relevant, divergent and druggable pathways (DNA repair and STAT3) that can be targeted in combination to effectively combat drug resistance. We also found that the same pathways that were deregulated in palbociclib-resistant cells were also altered in tumor samples obtained from patients who progressed while on palbociclib and endocrine therapy
提供机构：
UT MD Anderson Cancer Center
创建时间：
2022-02-20
