Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 13

Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with compound 13 Descriptor: (3P,5M)-3-{3-[(3,5-dichloropyridin-2-yl)oxy]phenyl}-5-(1H-tetrazol-5-yl)-2,1-benzoxazole, Inositol polyphosphate multikinase Authors: Wang, H, Shears, S.B. Deposit date: 2023-12-04 Release date: 2024-12-11 Last modified: 2025-12-10 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structural Rationalization of IPMK Inhibitor Potency. J.Med.Chem., 68, 2025人源肌醇磷酸多激酶核心催化结构域与化合物13复合物的晶体结构 配体描述：(3P,5M)-3-{3-[(3,5-二氯吡啶-2-基)氧基]苯基}-5-(1H-四唑-5-基)-2,1-苯并恶唑 肌醇多磷酸激酶（Inositol polyphosphate multikinase，IPMK） 作者：Wang, H、Shears, S.B. 存入日期：2023-12-04 发布日期：2024-12-11 最后修改日期：2025-12-10 实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.96埃（Å） 引用文献：《IPMK抑制剂效力的结构合理化阐释（Structural Rationalization of IPMK Inhibitor Potency）》，《药物化学杂志（J.Med.Chem.）》，第68卷，2025年