Summary of antagonistic hits identified from the AaDOP2 screen against the LOPAC1280 library.
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†Percent inhibition of receptor response in the presence of test compound relative to the SCH23390 control;*, SCH23390 “antagonist control”;‡, compound analyzed in cAMP confirmation assay; CDK, cyclin dependent kinase; DAR, dopamine receptor; H, histamine receptor; Lck, lymphocyte-specific protein tyrosine kinase; NOR, norepinephrine; mAChR, muscarinic acetylcholine receptor; Syk, spleen tyrosine kinase; σ, sigma receptor; 5-HT, 5-hydroxytryptamine (serotonin). N.D. = not determined.
创建时间：
2015-12-02
