Co-crystal structure of Chaetomium glucosidase with compound 11

Co-crystal structure of Chaetomium glucosidase with compound 11 Descriptor: (2R,3R,4R,5S)-1-{2-[4-(2-{[(5M)-3-chloro-5-(pyridazin-3-yl)phenyl]amino}ethyl)phenyl]ethyl}-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ... Authors: Karade, S.S, Mariuzza, R.A. Deposit date: 2022-09-02 Release date: 2023-02-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023毛壳菌（Chaetomium）α-葡萄糖苷酶与化合物11的共晶结构 描述符：(2R,3R,4R,5S)-1-{2-[4-(2-{[(5M)-3-氯-5-(哒嗪-3-基)苯基]氨基}乙基)苯基]乙基}-2-(羟甲基)哌啶-3,4,5-三醇、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、毛壳菌α-葡萄糖苷酶…… 作者：Karade S.S.、Mariuzza R.A. 提交日期：2022-09-02 发布日期：2023-02-22 最后修改日期：2024-11-13 检测方法：X射线衍射（2.25 Å） 引用文献：《具有抗SARS-CoV-2活性的内质网α-葡萄糖苷酶I强效亚氨基糖抑制剂的基于结构设计》，J.Med.Chem., 66, 2023