Organismal sensitivity to environmental agents induced toxicity: A comparative ecotoxicogenomics approach [Caenorhabditis elegans]. Caenorhabditis elegans

To understand the role of genetic makeup in organismal tolerance/susceptibility we compared the Caenorhabditis elegans transcriptome profiles with those of Drosophila melanogaster. In this study, we exposed both organisms, to a synthetic chemical and evaluated their response at the transcriptome level, to gain insights to molecular players/pathways underlying organismal tolerance/susceptibility to xenobiotics Overall design: Organism : Caenorhabditis elegans, Agilent's C.elegans Gene Expression 8x60k Array (AMADID: 052672) designed by Genotypic Technology Private Limited