Understanding the incidence and timing of rabies cases in domestic animals and wildlife in south-east Tanzania in the presence of widespread domestic dog vaccination campaigns

The “Zero by 30” strategic plan aims to eliminate human deaths from dog-mediated rabies by 2030, and domestic dog vaccination is a vital component of this strategic plan. In areas where domestic dog vaccination has been implemented, it is important to assess the impact of this intervention. Additionally, understanding temporal and seasonal trends in the incidence of animal rabies cases may assist in optimizing such interventions. Data on the incidence of probable rabies cases in domestic and wild animals were collected between January 2011 and December 2018 in thirteen districts of south-east Tanzania where jackals comprise over 40% of reported rabies cases. Vaccination coverage was estimated over this period, as five domestic dog vaccination campaigns took place in all thirteen districts between 2011 and 2016. Negative binomial generalized linear models were used to explore the impact of domestic dog vaccination on the annual incidence of animal rabies cases, whilst generalized additiv..., All data files are in CSV format. Details of data collection are provided within the paper. ,“‘到2030年清零’（Zero by 30）战略计划旨在于2030年前消除犬介导狂犬病导致的人类死亡病例，家养犬疫苗接种是该战略计划的核心构成要素。在已推行家养犬疫苗接种的地区，评估该干预措施的实际效果尤为关键。此外，明晰动物狂犬病病例发病的时间与季节变化趋势，可助力优化此类干预方案。 2011年1月至2018年12月期间，研究团队在坦桑尼亚东南部13个区县收集了家养动物与野生动物的疑似狂犬病病例发病数据——上述区县内胡狼占报告狂犬病病例总数的40%以上。2011年至2016年间，该13个区县累计开展了5次家养犬疫苗接种行动，本研究据此估算了同期的疫苗接种覆盖率。 本研究采用负二项分布广义线性模型（negative binomial generalized linear models），探究家养犬疫苗接种对动物狂犬病病例年发病率的影响；同时采用广义加性模型（generalized additive models）对相关趋势展开分析。 所有数据文件均采用CSV格式。 数据收集的详细细节已在相关论文中予以说明。