Endoscopic and histopathological findings in dyspeptic patients with Helicobacter pylori infection

Background: Despite advancements in medicine, gastrointestinal diseases caused by Helicobacter pylori continue to be common in developing countries. This study analyzed gastric mucosal biopsies from the Manipal College of Medical Sciences in Pokhara, Nepal, between January 2017 and June 2018 to determine the prevalence of H. pylori, its association with histopathological changes, and evaluate it using OLGA and OLGIM systems.
Methods: In this analytical cross-sectional study, 80 patients with dyspepsia were included. Biopsies were collected, stored, and labeled. The biopsies were fixed, cut into sections, and stained with routine H&E and Giemsa stains. Evaluations were made using OLGA and OLGIM staging. Statistical analyses were performed using SPSS version 17.0, with significance determined at p<0.05.
Results: Hospital-visiting patients had an 8.41% (38/452) [10.97–5.85%, 95% Confidence Interval (CI)] rate of H. pylori infection, while dyspeptic patients had 47.50% (38/80) (58.44..., Age, sex, and clinical diagnoses were noted in the patient information sheet, which was further entered into Microsoft Excel version 10.0.
The data analysis was conducted using the SPSS software, version 17.0. Descriptive statistics were calculated and presented in tables and figures. The Chi-Square test was used to determine the statistical significance of qualitative variables, with a p-value of <0.05 considered significant., , # Endoscopic and histopathological findings in dyspeptic patients with Helicobacter pylori infection

The dataset is of dyspeptic patients with and without Helicobacter pylori infection. Dataset comprises a single sheet. The sheet details for demographic information, such as age group and gender of the dyspeptic patients; clinical manifestations, including upper gastrointestinal bleeding, abdominal pain, anorexia, weight loss; endoscopic findings comprising erythema, ulcer, atrophy, growth; provisional endoscopic diagnoses, comprising gastritis, benign gastric ulcer, malignancy; histopathological diagnoses, corpus and antrum abnormalities, and Operative Link on Gastritis Assessment and Operative Link on Gastric Intestinal Metaplasia scoring and staging.

Exact or direct age is removed and is categorized as age group to anonymize the data.

Data were anonymized with the code. Patients with dyspepsia were coded with alphanumeric number with initial P i.e. Pno.

Units of the study varia...