Fragile X syndrome (FXS) is caused by transcriptional silencing of the FMR1 gene during embryonic development with the consequent loss of the encoded fragile X mental retardation protein (FMRP). The p
qPCR was carried out on 10 ng RNA from maturing neurons and neurons subjected to OGD to determine the purity of the primary cortical neuronal cultures. qPCR amplification was carried out for a maximum
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study are to compare the brain of atrn wildtype and homozygous adult zebrafi
Our work aims to characterize the role of Zrf1 in the generation and maintenance of neural progenitor cells (NPCs) Overall design: Gene expression profile of shCtrl and shZrf1 cells during generation