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Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex [Vero E6]

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NIAID Data Ecosystem2026-03-14 收录
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This study reports a screen to identify putative inhibitors of the eIF4F complex for potential effects on blocking coronavirus replication, using HCoV-OC43 (OC43) infection of Vero E6 cells and the lung epithelial cancer line A549 as models. Gene expression comparison of uninfected control, HCoV-OC43 infected, and HCoV-OC43 infected treated with compounds on Vero E6 cells using RNA-seq.

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2023-01-06
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