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Coproduct Promoted Povarov Reaction: Synthesis of Substituted Quinolines from Methyl Ketones, Arylamines, and α‑Ketoesters

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Figshare2016-02-13 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Coproduct_Promoted_Povarov_Reaction_Synthesis_of_Substituted_Quinolines_from_Methyl_Ketones_Arylamines_and_Ketoesters/2161111
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A highly efficient I2-catalyzed Povarov-type reaction of methyl ketones, arylamines, and α-ketoesters is developed. This reaction utilizes a catalytic amount of HI coproduct as a promoter for the synthesis of substituted quinolones. This simple procedure represents an interesting new form of reactivity for the Povarov reaction with good functional group compatibility.
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2016-02-13
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