Supplementary information for dissertation "CAR-T cells for Immunotherapy of Cancer"
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Supplementary information on the dissertation "CAR T cells for Immunotherapy of Cancer", with the following list of sub-papers: 1. Single-cell RNA analysis reveal subpopulations of CAR T cells correlating with response in lymphoma patients 2. Preclinical evaluation of CAR20(NAP)-T cells for B cell lymphoma 3. Complementary-determining region clustering causes CAR-T cell dysfunction 4. Armed CAR-T cells directed against IL13Rα2 show potent activity against glioblastoma Differentially expressed genes between responders and non-responders (Fc -1.2 ≤ or ≤ 1.2). The dataset was originally published in DiVA and moved to SND in 2024.
本数据集为学位论文《嵌合抗原受体T细胞(CAR T cells)用于癌症免疫治疗》的补充信息,附带如下子论文清单: 1. 单细胞RNA分析揭示淋巴瘤患者中与治疗应答相关的CAR-T细胞亚群 2. CAR20(NAP)-T细胞治疗B细胞淋巴瘤的临床前评价 3. 互补决定区(Complementary-determining region)聚类引发CAR-T细胞功能失调 4. 靶向IL13Rα2的武装型CAR-T细胞对胶质母细胞瘤展现强效抗肿瘤活性 应答者与非应答者之间的差异表达基因(Fc阈值为-1.2≤或≤1.2)。 本数据集最初发布于DiVA平台,并于2024年迁移至SND平台。



