PGE2-EP2/4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

Our research was EP2 and EP4 inhibition may suppress tumor growth in LLC1 syngeneic transplantation model through the modulation of inflammation and immune response. This dataset contains raw data of (1) the measurement of tumor size and calculation of tumor volume, (2) FACS experiments raw data files and quantification, (3) qPCR experiments raw data and quantification, (4) immunohistochemistry images and quantification data and (5) in vitro cell growth assay raw data that were used for making figures in our Cell Reports paper.

本研究发现，通过调节炎症和免疫反应，EP2和EP4抑制可能抑制LLC1同源移植模型中的肿瘤生长。本数据集包含以下原始数据：(1) 肿瘤大小测量和肿瘤体积计算，(2) 流式细胞术实验原始数据文件和量化结果，(3) 定量实时聚合酶链反应实验原始数据和量化结果，(4) 免疫组化图像及量化数据，以及(5) 用于Cell Reports论文中图表制作的体外细胞生长实验原始数据。