ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage/cGAS-STING activation

NIAID Data Ecosystem2026-05-01 收录

cGAS-STING信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE161924 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-11-18

Brucellosis Vaccine Ag85a-S2 activates cGAS-Sting Signaling Pathway in Intestinal Mucosal Cells. Brucellosis Vaccine Ag85a-S2 activates cGAS-Sting Signaling Pathway in Intestinal Mucosal Cells

疫苗免疫机制

cGAS-STING信号通路

Brucellosis is a zoonotic disease caused by Gram-negative bacteria, resulting in an economic loss of billions of USD per year. Most of the Brucellosis vaccines in the application are the whole bacteri

NIAID Data Ecosystem50

ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage/cGAS-STING activation [B16 vivo]

肿瘤免疫治疗

cGAS-STING信号通路

Novel approaches are needed to boost the efficacy of immune checkpoint blockade (ICB) therapy. Ataxia Telangiectasia Mutated (ATM) protein plays a central role in sensing DNA double strand breaks an

NIAID Data Ecosystem30

Gene expression in lung tissue, blood and spleen of mice with severe acute pancreatitis

胰腺炎分子机制

cGAS-STING信号通路

Severe acute pancreatitis (SAP) is a critical disease, often complicated with multiple organ dysfunction, which seriously endangeres the life safety of patients. Previous studies have shown that cGAS-

NIAID Data Ecosystem10

Structure of VACV Poxin in post-reactive state with Gp[2'-5']Ap[3']

病毒蛋白结构

cGAS-STING信号通路

Structure of VACV Poxin in post-reactive state with Gp[2'-5']Ap[3'] Descriptor: 2',5'-GpAp, Protein B2 Authors: Eaglesham, J.B, Kranzusch, P.J. Deposit date: 2018-08-02 Release date: 2019-02-06 Last m

Protein Data Bank Japan2024-03-13 更新40

cGAS Senses Translation Stress Through Direct Binding to Ribosomes

cGAS-STING信号通路

翻译应激感知

The cGAS-STING pathway, a central component of the innate immune system, senses cytosolic DNA and induces interferon-stimulated genes (ISGs) to mediate inflammation. Here we report the unexpected disc

NIAID Data Ecosystem30

ATM inhibition enhances cancer immunotherapy by promoting mtDNA leakage/cGAS-STING activation

资源简介：

相关数据集