Association of rs10846744 with CV events in STABILITY and SOLID-TIMI 52 studies.

In STABILITY, multivariable regression models included adjustment for age, sex, region, BMI, hyperlipidemia, statin use, baseline LDL, baseline HDL, eGFR, smoking, diabetes, prior MI, principal components (PCs) of ancestry and randomized treatment arm. In SOLID-TIMI 52, multivariable regression models included adjustment for age, sex, region, BMI, hyperlipidemia, statin use, baseline LDL, baseline HDL, eGFR, smoking, diabetes, prior MI, index diagnosis (STEMI vs not), days from qualifying event, PCs of ancestry and randomized treatment arm. Genetic associations are shown for rs10846744 effect allele C (vs. reference allele G).