Described herein is the development of a desaturation and β-fluorination reaction of cyclic amides, which is achieved by an oxidative-promoted selective hydrogen atom-transfer/isomerization/electrophi
Preprocessed NMR spectra of 53 cats when healthy (H) and six weeks later when experimental asthma has been induced (A). The preprocessing steps were probabilistic quotient normalization and glog trans
The first palladium-catalyzed asymmetric allylic trifluoromethylation is disclosed. The methodology evokes a fundamental principle by which the synergistic interplay of a leaving group and its subsequ
An oxy-palladation, formal Wagner–Meerwein rearrangement and fluorination cascade has been established for generating fluorinated oxazolidine-2,4-diones and oxazolidin-2-ones. The reaction has a broad
A direct fluorination of 4,6-disubstituted 2-aminopyrimidines with Selectfluor in the presence of Ag(I) is presented, affording the corresponding 4,6-disubstituted 5-fluoro-2-aminopyrimidines with ac
