Association statistics and effects of 203 lead SNPs
收藏DataCite Commons2020-08-26 更新2024-07-27 收录
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https://figshare.com/articles/LocusZoom_plots_and_effects_of_203_lead_SNPs/9825071/2
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For each SNP, the mat file contains the RSID, chromosome and hg19 position, canonical correlation values, CCA coefficients, meta-analysis p-values, degrees of freedom, the p-value from the CCA step, and the p-value from the regression of slopes. Values from the US-driven meta-analysis are in the first column and values from the UK-driven meta-analysis are in the second column. <br><br>For each SNP, the pdf file contains: (A) -log<sub>10</sub>(p-value) of the meta-analysis p-values per facial segment in META<sub>US</sub> and META<sub>UK</sub>. Black-encircled facial segments have reached a genome-wide p-value (p <= 5 x 10<sup>-8</sup>). (B) The normal displacement (displacement in the direction locally normal to the facial surface) in each quasi-landmark of the facial segment reaching the lowest p-value in META<sub>US</sub> and META<sub>UK </sub>going from the minor to the major allele SNP variant. Blue: inward depression; Red: outward protrusion. (C) LocusZoom plots in META<sub>US</sub> (top) and META<sub>UK</sub> (bottom). Points are color-coded based on linkage disequilibrium (r<sup>2</sup>) in the 1000G Phase 3 EUR super-population. Asterisks represent genotyped SNPs, circles represent imputed SNPs.
提供机构:
figshare
创建时间:
2019-09-19



