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Investigation of ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines

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NIAID Data Ecosystem2026-05-01 收录
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We identified that upregulation of ST8SIA1 promotes melanoma brain metastasis. The goal of this RNA-seq is to analyze the ST8SIA1 expression in icaritin-treated and untreated melanoma cell lines (DP-0574 and WP-0614 cell lines) In vitro functional studies demonstrate that ST8SIA1 overexpression promotes cell proliferation and colony formation and that this can be halted by icaritin treatment. mRNA profiles of icaritin-treated or control untreated cells were generated by deep sequencing using Illumina NextSeq 550, in triplicate.

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2024-04-30
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