Additional file 6 of The effects of model complexity and size on metabolic flux distribution and control: case study in Escherichia coli

Additional file 6. Analysis of absolute deviations in means of flux control coefficients for the entire systems. The mean flux control coefficient $$C_p^v$$ C p v is first computed based on the populations of 50’000 models for D1-3 for all enzymatic reactions with respect to all the enzymes. The absolute deviation between these means of control coefficients is compared pairwise for D1 and D2, and D2 and D3. The vertical corresponds to the reactions v and the horizontal to the enzymes p. A large deviation indicates a discrepancy in the prediction of the model for that given control coefficient $$C_p^v$$ C p v .