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Prolyl Hydroxylase Inhibition and HIF-dependent Metabolic Reprogramming Protects Against Lethal SARS-CoV-2 Infection

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DataCite Commons2022-10-03 更新2024-07-29 收录
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https://figshare.com/articles/dataset/Prolyl_Hydroxylase_Inhibition_and_HIF-dependent_Metabolic_Reprogramming_Protects_Against_Lethal_SARS-CoV-2_Infection/21266208/1
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Data is total sum normalized targeted metabolomics data from B6.Cg-Tg(K18-ACE2)2Prlmn/J mice (K18-hACE2) lungs. Data was collected as part of two seperate experiments designated by Exp413 and Exp415. Data was collected at day 3 and day 5 post infection with SARS-CoV-2 with or without treatment with the Prolyl Hydroxylase inhibitor DMOG. Data was collected as referenced in JCI Insight. 2022;7(2):e155896.https://doi.org/10.1172/jci.insight.155896. Methodology was based on the method established by McCloskey et. al. in https://doi.org/10.1007/s11306-015-0790-y.
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figshare
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2022-10-03
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