Histone Deacetylase Inhibition Promotes Osteoblast Maturation by Altering the Histone 4 (H4) Epigenome

NIAID Data Ecosystem2026-03-07 收录

组蛋白去乙酰化酶抑制剂

成骨细胞成熟

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA217927 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

创建时间：

2013-09-03

A novel multistage antiplasmodial inhibitor targeting Plasmodium falciparum histone deacetylase 1. Plasmodium falciparum

抗疟疾药物靶点

组蛋白去乙酰化酶抑制剂

Although artemisinin combination therapies have succeeded in reducing the global burden of malaria, multidrug resistance of the deadliest malaria parasite, Plasmodium falciparum, is emerging worldwide

NIAID Data Ecosystem80

Histone Deacetylase Inhibitors Global Market Report 2024

组蛋白去乙酰化酶抑制剂

市场分析

Global histone deacetylase inhibitors market size is expected to reach $1.64 billion by 2028 at a rate of 8.0%, segmented as by classification, class i histone deacetylases (hdacs), class ii histone d

www.thebusinessresearchcompany.com60

X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition. X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition

神经肌肉疾病治疗

组蛋白去乙酰化酶抑制剂

X-linked myotubular myopathy (XLMTM) is a fatal neuromuscular disorder caused by loss of function mutations in MTM1 . At present, there are no directed therapies for XLMTM, and incomplete understandin

NIAID Data Ecosystem50

A novel histone deacetylases inhibitor exerts promising anti-breast cancer activity via triggering AIFM1-dependent programmed necrosis. A novel histone deacetylases inhibitor exerts promising anti-breast cancer activity via triggering AIFM1-dependent programmed necrosis

癌症靶向治疗

组蛋白去乙酰化酶抑制剂

Breast cancer is one of the most lethal cancers in women, and its resistance to chemotherapy remains a challenging problem. Histone deacetylases inhibitors (HDACIs) are a promising therapeutic tool fo

NIAID Data Ecosystem60

HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates

组蛋白去乙酰化酶抑制剂

靶向药物开发

The zinc-containing histone deacetylase enzyme HDAC7 is emerging as an important regulator of immunometabolism and cancer. Here, we exploit a cavity in HDAC7, filled by Tyr303 in HDAC1, to derive new

NIAID Data Ecosystem60

Histone Deacetylase Inhibition Promotes Osteoblast Maturation by Altering the Histone 4 (H4) Epigenome

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