Gene expression profiling of IL7R+PIR+ and IL7R-PIR- subsets in LIN-c-Kit+ E12.5 mouse fetal liver cells

In order to find out target genes of Runx/Cbfb2 complexes in PIR+IL7R+ subset. In particular, genes that would explain why the size of thymus was small by lack of Cbfb2. Upon finding of decreased IL7R+PIR+ subset, which was reported as thymus-homing progenitor, in Cbfb2 deficient embryos, we focused on these population. Examination of wild type and knock out in 2 cell types.