Supplementary datasets: Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis, Savitski et al.
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Savitski et al Figure 2.zip Description: mPDP of THP1 cells treated with JQ1-VHL PROTAC Content: - Figure 2.pdf - Figure S2.pdf - Supplementary dataset 1_mPDP JQ1-VHL PROTAC.xlsx Savitski et al Figure 3.zip Description: 2-dimensional Thermal proteome profiling (2D-TPP) of THP1 cells treated with JQ1 Content: - Figure 3.pdf - Figure S3.pdf - Supplementary dataset 1_mPDP JQ1-VHL PROTAC.xlsx Savitski et al Figure 4.zip Description: mPDP of estrogen signaling and selective estrogen receptor modulators (SERMs) Content: - Figure 4.pdf - Figure S4.pdf - Supplementary Dataset 3_Estrogen.xlsx Savitski et al Figure 5.zip Description: mPDP of HSP inhibitor 17-AAG in Jurkat and MCF7 cells Content: - Figure 5.pdf - Figure S5.pdf - Supplementary Dataset 3_Estrogen.xlsx - Supplementary Dataset 4_17AAG.xlsx - Supplementary Dataset 5_HSP90 dep etc.xlsx - Supplementary Dataset 6_reference_melting curves.xlsx - Supplementary Dataset 7_kinobeads_activatedLysate.xlsx Savitski et al Figure 6-7.zip Description: mPDP of HSP inhibitor 17-AAG in primary T-cells Content: - Figure 6.pdf - Figure S6.pdf - Figure 7.pdf - Figure S7.pdf - Supplementary Dataset 5_HSP90 dep etc.xlsx - Supplementary Dataset 6_reference_melting curves.xlsx - Supplementary Dataset 8_Tcells.xlsx
Savitski等人 图2.zip 描述：经JQ1-VHL蛋白水解靶向嵌合体（PROTAC）处理的THP1细胞的mPDP实验数据 包含文件： - 图2.pdf - 补充图2.pdf - 补充数据集1_mPDP JQ1-VHL PROTAC.xlsx Savitski等人 图3.zip 描述：经JQ1处理的THP1细胞的二维热蛋白质组分析（2D-TPP）实验数据 包含文件： - 图3.pdf - 补充图3.pdf - 补充数据集1_mPDP JQ1-VHL PROTAC.xlsx Savitski等人 图4.zip 描述：雌激素信号通路与选择性雌激素受体调节剂（SERMs）的mPDP实验数据 包含文件： - 图4.pdf - 补充图4.pdf - 补充数据集3_雌激素.xlsx Savitski等人 图5.zip 描述：Jurkat与MCF7细胞中热休克蛋白（HSP）抑制剂17-AAG的mPDP实验数据 包含文件： - 图5.pdf - 补充图5.pdf - 补充数据集3_雌激素.xlsx - 补充数据集4_17AAG.xlsx - 补充数据集5_HSP90依赖相关等.xlsx - 补充数据集6_参考熔解曲线.xlsx - 补充数据集7_激酶磁珠活化裂解液.xlsx Savitski等人 图6-7.zip 描述：原代T细胞中热休克蛋白（HSP）抑制剂17-AAG的mPDP实验数据 包含文件： - 图6.pdf - 补充图6.pdf - 图7.pdf - 补充图7.pdf - 补充数据集5_HSP90依赖相关等.xlsx - 补充数据集6_参考熔解曲线.xlsx - 补充数据集8_T细胞.xlsx
