Mechanochemically modified biogenic silica with Zn-Al domains for reversible imatinib adsorption and continuous-flow recovery

This dataset contains the experimental data supporting the study “Mechanochemically modified biogenic silica with Zn-Al domains for reversible imatinib adsorption and continuous-flow recovery.” The work investigates the adsorption, recovery, regeneration, and continuous-flow retention of imatinib mesylate (IM) using a Zn-Al-modified biogenic silica derived from rice husk. The dataset includes raw and processed data corresponding to HPLC calibration and analytical validation, preliminary adsorption experiments, effects of adsorbent dosage, solution pH, and stirring speed, adsorption kinetics at different initial IM concentrations, equilibrium isotherms at 288.15–323.15 K, and thermodynamic calculations. It also contains data from coexisting cation and anion experiments, adsorption in real aqueous matrices, desorption screening, regeneration over ten consecutive adsorption-desorption cycles, adsorbent mass recovery, and Zn and Al leaching determined by ICP-OES. Additionally, continuous-flow fixed-bed data are provided, including the experimental breakthrough curve, effective flow-rate determination, breakthrough and saturation times, dynamic adsorption capacities, mass-transfer-zone calculations, acidic column desorption, IM recovery, and concentration enhancement during elution.本数据集包含支撑题为《用于可逆吸附伊马替尼甲磺酸盐及连续流回收的含Zn-Al结构域的机械化学改性生物源二氧化硅》的研究的实验数据。该项研究以稻壳衍生的Zn-Al改性生物源二氧化硅为吸附剂，探究了伊马替尼甲磺酸盐（imatinib mesylate，IM）的吸附、回收、再生及连续流滞留性能。数据集涵盖高效液相色谱（High Performance Liquid Chromatography，HPLC）校准与分析验证、初步吸附实验、吸附剂投加量、溶液pH值及搅拌转速的影响规律、不同初始IM浓度下的吸附动力学、288.15~323.15 K温度区间内的平衡等温线及热力学计算相关的原始与处理后数据。此外还包含共存阳离子与阴离子实验、真实水基质中的吸附实验、解吸筛选、连续十次吸附-解吸循环后的再生性能、吸附剂质量回收率，以及通过电感耦合等离子体发射光谱仪（Inductively Coupled Plasma Optical Emission Spectrometry，ICP-OES）测定的Zn、Al浸出量相关数据。此外还提供了连续流固定床实验数据，包括实验突破曲线、有效流速测定、突破与饱和时间、动态吸附容量、传质区计算、酸性柱洗脱、IM回收及洗脱过程中的浓度富集数据。