Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor

NIAID Data Ecosystem2026-05-01 收录

HCVNS5B聚合酶结构

抗HCV药物设计

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Crystal structure of HCV NS5B RNA polymerase complexed with a tetracyclic inhibitor

创建时间：

2023-10-25

Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor

病毒蛋白结构解析

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Crystal structure of hepatitis C virus NS3 helicase with a novel inhibitor Descriptor: Genome polyprotein, N-[4-(BIS{4-[(3-SULFOPHENYL)AMINO]PHENYL}METHYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE]-4-SULFOBENZE

Protein Data Bank Japan2023-11-01 更新60

Crystal structure of hcv ns5b polymerase in complex with compound 12

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蛋白质-配体复合物结构

Crystal structure of hcv ns5b polymerase in complex with compound 12 Descriptor: 6-[3-(pyridin-2-yl)-2-(trifluoromethyl)phenoxy]-1-(2,4,6-trifluorobenzyl)quinazolin-4(1H)-one, GLYCEROL, Genome polypro

Protein Data Bank Japan2024-11-06 更新50

BindingDB Entry 50018890: 2015 Philip S. Portoghese Medicinal Chemistry Lectureship. Curing Hepatitis C Virus Infection with Direct-Acting Antiviral Agents: The Arc of a Medicinal Chemistry Triumph.

药物靶点识别

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Small molecule binding data for protein Nuclear receptor subfamily 1 group I member 2, Platelet-derived growth factor receptor alpha/beta, and RNA-directed RNA polymerase, Uniprot O75469, P05622, P266

DataCite Commons2024-04-26 更新30

HCV NS5B GT1A C316Y with GSK5852

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结构生物学

HCV NS5B GT1A C316Y with GSK5852 Descriptor: NS5B RNA-dependent RNA polymerase, SULFATE ION, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-

Protein Data Bank Japan2024-03-13 更新60

The structure of HCV NS3 helicase (Heli-80) bound with inhibitor ITMN-3479

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蛋白质-配体复合物结构

The structure of HCV NS3 helicase (Heli-80) bound with inhibitor ITMN-3479

NIAID Data Ecosystem50