Genome-wide de novo L1 Retrotransposition Connects Endonuclease Activity with Replication: creating new models

This data repository provides code and general instructions for creating new LINE-1 (L1) insertion site models as described in Flasch, et al., 2019:https://www.sciencedirect.com/science/article/pii/S0092867419302338?via%3Dihub

Please see file L1_Simulation_Files_help.docx for more detailed information.

File L1Simulation_filelist.xlsx lists the files described in the Word file and found in L1Simulations.tar.gz.

Required large file ChrmsALL_table_sortEN.bed.gz is found individually. Importantly, like the paper analysis, this file is specific to the hg19 version of the human genome.

Please see the companion Zenodo data set10.5281/zenodo.8233858if you only want to access our insertion data and the resulting models we created.