DDB1-CRBN with CK1 alpha, SB-405483, and DEG-47: composite map and model submission
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DDB1-CRBN with CK1 alpha, SB-405483, and DEG-47: composite map and model submission Descriptor: Casein kinase I isoform alpha, DNA damage-binding protein 1, N-[3-(benzyloxy)pyridin-2-yl]-N'-(4-cyano-2-hydroxyphenyl)urea, ... Authors: Rizvi, Z, Lander, G.C. Deposit date: 2025-05-27 Release date: 2025-11-19 Last modified: 2026-03-25 Method: ELECTRON MICROSCOPY (3 Å) Cite: Identification of an allosteric site on the E3 ligase adapter cereblon. Nature, 651, 2026
DDB1-CRBN结合CK1α、SB-405483与DEG-47:复合图谱与模型提交 描述符:酪蛋白激酶I亚型α(Casein kinase I isoform alpha)、DNA损伤结合蛋白1(DNA damage-binding protein 1)、N-[3-(苄氧基)吡啶-2-基]-N'-(4-氰基-2-羟基苯基)脲,…… 作者:Rizvi, Z、Lander, G.C. 提交日期:2025-05-27 发布日期:2025-11-19 最后修改日期:2026-03-25 实验方法:电子显微镜(3 Å) 引用文献:《E3连接适配器蛋白cereblon的变构位点鉴定》,《自然》,651卷,2026年



