Erianin inhibits the progression of pancreatic cancer by directly targeting AKT and ASK1

Erianin, a natural product extracted from Dendrobium, possesses multiple pharmacological properties, including antioxidative and antitumor activities. The objective of this study was: to evaluate the anti-pancreatic cancer activity of erianin and explore its underlying mechanisms.To further explore the potential molecular mechanisms of erianin in pancreatic cancer, we performed RNA Sequencing analysis to identify DEGs under erianin stimulation in SW1990 cells. SW1990 cells were treated with 100nM Erianin for 48 hours, with an equal concentration of DMSO as the control.