Analysis of livers of male and female B6C3F1 mice exposed to prototype treatments from five classes of model hepatotoxicants. These hepatotoxicants include compounds that activate the peroxisome prol

NIAID Data Ecosystem60

Study of the hepatoprotective activity of flavonoides on ethanol-induced injury in HepG2 cells

肝保护活性

乙醇诱导肝损伤

The goal of this study is to evaluate the potential protective effects of flavonoids, which exist in Chinese propolis, on ethanol-induced injury in HepG2 cells. This in vitro study investigated the pr

NIAID Data Ecosystem40

Liver expression data from 31 mouse strains treated with vehicle or isoniazid for 3 days

肝损伤机制

多品系小鼠基因表达

Isoniazid induced varying degrees of hepatic steatosis in an inbred strain Mouse Diversity Panel (MDP) study. RNA was isolated from all animals for analysis of gene expression changes in the liver. Th

NIAID Data Ecosystem70

A well-characterized mechanistic Model for exploring known or hypothesized T cell -mediated drug induced liver injury: current capabilities and challenges for future predictivity

乙醇诱导肝损伤

系统毒理学

Drug-induced liver injury (DILI) is an adverse event whose emergence can slow or halt drug development programs. Adaptive immune responses have been implicated for several DILI compounds, and drug-spe

DataCite Commons2025-05-23 更新50

Gene expression in the liver of ethanol-treated mice via gastric tube in multiple strains

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