human dihydrofolate reductase complex with NADPH and 5-methyl-6-(2',3',4'-trifluorophenylthio)thieno[2,3-d]pyrimidine-2,4-diamine
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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human dihydrofolate reductase complex with NADPH and 5-methyl-6-(2',3',4'-trifluorophenylthio)thieno[2,3-d]pyrimidine-2,4-diamine Descriptor: 5-methyl-6-[(2,3,4-trifluorophenyl)sulfanyl]thieno[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Cody, V. Deposit date: 2016-01-22 Release date: 2017-01-25 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.46 Å) Cite: Human dihydrofolate reductase ternary complex with a series of fluorine substituted 5-methyl-6-phenythio)thieno[2,3-d]pyrimidine-2,4-diamines To Be Published
人类二氢叶酸还原酶(dihydrofolate reductase)与烟酰胺腺嘌呤二核苷酸磷酸(NADPH)及5-甲基-6-(2',3',4'-三氟苯硫基)噻吩并[2,3-d]嘧啶-2,4-二胺的复合物
描述符:5-甲基-6-[(2,3,4-三氟苯基)硫基]噻吩并[2,3-d]嘧啶-2,4-二胺、二氢叶酸还原酶(dihydrofolate reductase)、烟酰胺腺嘌呤二核苷酸磷酸(NADPH)
作者:科迪(Cody, V.)
存放日期:2016年1月22日
发布日期:2017年1月25日
最后修改日期:2023年9月27日
实验方法:X射线衍射(X-RAY DIFFRACTION,分辨率1.46埃)
引用信息:含系列氟取代5-甲基-6-苯硫基噻吩并[2,3-d]嘧啶-2,4-二胺的人类二氢叶酸还原酶三元复合物 待发表
创建时间:
2016-01-22



