CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH Compound-12 (AKA; 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyrid

CRYSTAL STRUCTURE OF MYELOPEROXIDASE SUBFORM C (MPO) COMPLEX WITH Compound-12 (AKA; 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyrid Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-benzyl-1H-[1,2,3]triazolo[4,5-b]pyridin-5-amine, CALCIUM ION, ... Authors: Khan, J.A. Deposit date: 2020-05-12 Release date: 2020-10-14 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase. Bioorg.Med.Chem., 28, 2020

髓过氧化物酶亚型C（myeloperoxidase, MPO）与化合物12（又名：7-苄基-1H-[1,2,3]三唑并[4,5-b]吡啶-5-胺）复合物的晶体结构。组分描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、7-苄基-1H-[1,2,3]三唑并[4,5-b]吡啶-5-胺、钙离子等。作者：Khan, J.A.。提交日期：2020-05-12；发布日期：2020-10-14；最后修改日期：2024-10-23。实验方法：X射线衍射（分辨率2.55埃）。引用文献：《7-苄基三唑并吡啶类作为髓过氧化物酶稳定、选择性可逆抑制剂的发现及其构效关系》，发表于《Bioorg. Med. Chem.》2020年第28卷。