C. difficile and the host fecal microbiota in domestic animals

Carriage of Clostridioides difficile in domestic animals has been linked with community-acquired C. difficile infection in humans. The goal of this study was to determine the prevalence of C. difficile in different domestic animals and associations between C. difficile presence and the host fecal microbiota. This BioProject contains community sequencing data from amplicon sequencing of the V4 region of the 16S rRNA gene of fecal samples from 197 animals (105 Canine, 70 Equine, 15 Feline, 5 Ovine, 1 Alpaca, and 1 Avian) collected at the North Carolina State University Veterinary Hospital. Host metadata and the results of laboratory assays for C. difficile presence, toxin profiling, and strain typing are included.