Mutational Analysis of the Phosphate-Binding Loop of Rhizobium meliloti DctD, a ς(54)-Dependent Activator
收藏PubMed Central2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC107239/
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资源简介：
The phosphate-binding loop of ς(54)-dependent activators is thought to participate in ATP binding and/or hydrolysis. Alanine substitutions at positions 3, 4, 6, 7, and 8 of this motif in Rhizobium meliloti DctD disrupted transcriptional activation and ATP hydrolysis. Interestingly, substitution of alanine at position 7 also affected DNA binding.
提供机构：
American Society for Microbiology (ASM)
